UP TO DATE ON Thyroid eye disease NOVEL INSIGHTS AND TREATMENT

Milano, 8-9 settembre 2023
SEDE: Aula Granelli
Padiglione Granelli-Marcora
Policlinico, Ospedale Maggiore
Via Francesco Sforza 35 – Milano

 

FRIDAY, SEPTEMBER 8TH

 

2.00 pm / Welcoming address and presentation of the Symposium

 

The role of microbiota in Graves’ disease and associated orbitopathy
2.30 pm / Experimental evidence from a mouse model of TED – Giulia Masetti (IT)
2.50 pm / Evidence in humans – Marian Ludgate (UK)

 

Blockade of the IGF-1 receptor: studies with linsitinib
3.10 pm / Linsitinib treatment in a mouse model of TED – Anja Eckstein (DE)
3.30 pm / The VGN-TED 301 trial: an update – Raymond Douglas (US)

 

3.50 pm / Coffee break

 

Anti-TSHr blockade and novel immunosuppressants in active TED
4.20 pm / K1-70 targeting of the TSH receptor – Jane Sanders (UK)
4.40 pm / Belimumab (anti-BAFF) in active TED – Irene Campi (IT)
4.55 pm / Rationale and efficacy of Sirolimus treatment in TED – Michele Marinò (IT)

 

Ongoing Randomized Controlled Trials in TED
5.10 pm / The IMVT-1401-3201/3203 trials: rationale – Marius Stan (US)
5.30 pm / Tocilizumab in active TED: the Italian multicenter trial – Ilaria Muller (IT)
5.50 pm / The VRDN – 001 clinical trial: an update – Raymond Douglas (US)

 

6.10 pm / Discussion and conclusion

 

SATURDAY, SEPTEMBER 9TH

 

8.50 am / Reconvening of the Symposium

 

Experience with Teprotumumab in a US Multidisciplinary TED clinic
9.00 am / Introduction of Teprotumumab & Endocrine Considerations
Chrysoula Dosiou (US)
9.20 am / Ophthalmic Considerations for Teprotumumab Therapy
Andrea Kossler (US)
9.40 am / The safety profile of Teprotumumab – Marius Stan (US)

 

Assessment of treatment outcomes in TED: are the tools of the trade fit for purpose?
10.00 am / Outcomes of efficacy: inflammation, proptosis or both? – Luigi Bartalena (IT), Marius Stan (US), Petros Perros (UK)

 

10.40 am / Coffee break

 

Update on the surgical treatment of TED
11.00 am / Endoscopic orbital surgery for dysthyroid optic neuropathy – Claudio Guastella (IT)
11.20 am / Ophthalmological/surgical integrated management of dysthyroid optic neuropathy – Nicola Currò (IT)
11.35 am / Neuronavigation in orbital surgery – Lelio Baldeschi (IT)

 

Round table Prevention of TED
11.50 am / Preventable risk factors – Maria Laura Tanda (IT)
12.00 pm / The TEARS proposal – Lelio Baldeschi (IT), Anja Eckstein (DE), Petros Perros (UK)
12.20 pm / The Milan Pledge – Mario Salvi (IT)

 

12.30 pm / Concluding remarks